Publications
May,
2013
Cortical Neurons Culture To Study C-Jun N-Terminal Kinase Signaling Pathway
Sclip A, Antoniou X, Borsello T
Protein Kinase Technologies Neuromethods Volume 68, 2012, Pp 189-202, May 2013 …
April,
2013
Soluble Aβ Oligomers-induced Synaptopathy: C-Jun N-terminal Kinase's Role.
Sclip A, Arnaboldi A, Colombo I., Veglianese P., Colombo L, Messa M., Mancini S., Cimini S., Antoniou X, Welker E., Salmona M, Borsello T
Http://www.ncbi.nlm.nih.gov/pubmed/23606726, April 2013
February,
2013
An N-terminal Fragment Of The Prion Protein Binds To Amyloid-β Oligomers And Inhibits Their Neurotoxicity In Vivo.
Fluharty RB, Biasini E, Stravalaci M, Sclip A, Diomede L, Balducci C, La Vitola P, Messa M, Colombo L, Forloni G, Borsello T, Gobbi M, Harris DA
J Biol Chem., February 2013
January,
2013
The Neurodegeneration In Alzheimer Disease And The Prion Protein.
Forloni G, Sclip A, Borsello T, Balducci C
Prion. 2013 Jan 1;7, January 2013 …
April,
2012
Contribution Of Serine Racemase/D-serine Pathway To Neuronal Apoptosis.
Esposito S., Pristerà A., Maresca G., Cavallaro S., Felsani A., Florenzano F., Manni L., Ciotti MT, Pollegioni L., Borsello T, Canu N
Aging Cell, April 2012 …
March,
2012
Specific Inhibition Of The JNK Pathway Promotes Locomotor Recovery And Neuroprotection After Mouse Spinal Cord Injury.
Repici M, Chen X., Morel PM, Doulazmi M, Sclip A, Cannaya V, Velgianese P., Kraftsik R, Mariani J, Borsello T, Dusart I
Neurobiol Dis, March 2012 …
January,
2012
The JNK Signalling Transduction Pathway In The Brain.
Antoniou X, Borsello T
Front Biosci (Elite Ed). 2012 Jan 1;4:2110-20., January 2012 …
December,
2011
Crosstalk Between JNK And SUMO Signaling Pathways: DeSUMOylation Is Protective Against H2O2-induced Cell Injury
Feligioni M., Brambilla E, Camassa A, Sclip A, Arnaboldi A, Morelli F, Antoniou X, Borsello T
Plos One, December 2011
November,
2011
C-Jun N-terminal Kinase Regulates Soluble Abeta Oligomers And Cognitive Impairment In An AD Mouse Model
Sclip A, Antoniou X, Colombo A, Camici GG, Pozzi L, Cardinetti D, Feligioni M., Veglianese P., Bahlmann FH, Cervo L., Costa C., Tozzi A., Calabresi P., Forloni G, Borsello T
JBC, November 2011 …
June,
2011
JNK Plays A Key Role In Tau Hyperphosphorylation In Alzheimer's Disease Models
Ploia C, Antoniou X, Sclip A, Grande V, Cardinetti D, Colombo A, Canu N, Benussi L, Ghidoni R, Forloni G, Borsello T
J Alzheimers Dis., June 2011 …
February,
2011
JNK3 As A Therapeutic Target For Neurodegenerative Diseases.
Antoniou X, Falconi M., Di Marino D., Borsello T
J Alzheimers Dis. 2011 Feb 14, February 2011 …
January,
2011
C-Jun N-Terminal Kinase (JNK) And P38 Play Different Roles In Age-Related Purkinje Cell Death In Murine Organotypic Culture
Repici M, Wehrlé R, Antoniou X, Borsello T, Dusart I
Cerebellum. 2010 Dec 30, January 2011 …
October,
2010
A New Fluorogenic Peptide Determines Proteasome Activity In Single Cells
Urru S., Velgianese P., De Luigi A., Fumagalli E., Erba E., Gonella Diaza R., Carrà A., Davoli E., Borsello T, Forloni G, Pengo N., Cascio P., Cenci S., Sitia R., Salmona M
J Of Mecidal Chemistry, October 2010 …
September,
2010
January,
2010
Cell Permeable Peptides: A Promising Tool To Deliver Neuroprotective Agents In The Brain
Antoniou X, Borsello T
Pharmaceuticals ISSN 1424-8247, January 2010 …
January,
2010
Synthetic Amyloid-beta Oligomers Impair Long-term Memory Independently Of Cellular Prion Protein
Balducci C, Begg M, Stravalaci M, Bastone A, Sclip A, Biasini E, Tapella L, Colombo L, Manzoni C, Borsello T, Chiesa R, Gobbi M, Salmona M, Forloni G
Www.pnas.org/cgi/content/full/, January 2010 …
January,
2010
Role Of Glycogen Synthase Kinase-3beta In APP Hyperphosphorylation Induced By NMDA Stimulation In Cortical Neurons
Ploia C, Sclip A, Colombo A, Repici M, Gardoni F, Forloni G, Antoniou X, Borsello T
Www.mdpi.com/journal/pharmaceuticals, January 2010 …
December,
2009
JNK Contributes To Hif-1αlfa Regulation In Hypoxic Neurons
Antoniou X, Sclip A, Ploia C, Colombo A, Moroy G, Borsello T
Mdpi.com/journal/molecules, December 2009 …
August,
2009
C-Jun N-Terminal Kinase Pathway Activation In Human And Experimental Cerebral Contusion.
Ortolano F, Colombo A, Zanier ER, Sclip A, Longhi L, Perego C, Stocchetti N, Borsello T, De Simoni MG
J Neuropathol Exp Neurol. 2009 Aug 12., August 2009 …
March,
2009
INHIBITION OF C-JUN N-TERMINAL KINASE AFTER HEMORRHAGE BUT BEFORE RESUSCITATION MITIGATES HEPATIC DAMAGE AND THE INFLAMMATORY RESPONSE IN FEMALE RATS.
Relja B, Schwestka B, Lee VS, Henrich D, Czerny C, Borsello T, Manzi I, Lehnert M
Shock, March 2009 …
January,
2009
JNK Regulates APP Cleavage And Degradation In A Model Of Alzheimer's Disease
Colombo A, Bastone A, Ploia C, Sclip A, Salmona M, Forloni G, Borsello T
Neurobiology Of Disease, January 2009 …
January,
2009
JNK-binding Domain (JBD) -dependent Phosphorylation Of MKK4 And MKK7 And Balancing Cross-talk Between JNK And ERK Pathways In Cortical Neurons
Repici M, Mare L, Colombo A, Ploia C, Sclip A, Bonny C, Nicod P, Salmona M, Borsello T
Neuroscience, January 2009 …
December,
2008
Specific JNK Inhibition By D-JNKI1 Protects Purkinje Cells From Cell Death In Lurcher Mutant Mouse.
Repici M, Zanjani HS, Gautheron V, Borsello T, Dusart I, Mariani J
Cerebellum, December 2008 …
December,
2008
A Peptide Inhibitor Of C-jun N-terminal Kinase Modulates Hepatic Damage And The Inflammatory Response After Hemorrhagic Shock And Resuscitation.
Lehnert M, Relja B, Sun-Young Lee V, Schwestka B, Henrich D, Czerny C, Froh M, Borsello T, Manzi I
Shock, December 2008
March,
2008
Recombinant Human TNF-binding Protein-1 (rhTBP-1) Treatment Delays Both Symptoms Progression And Motor Neuron Loss In The Wobbler Mouse.
Bigini P, Repici M, Cantarella G, Fumagalli E, Barbera S, Cagnotto A, De Luigi A, Tomasi S, Bernardini R, Borsello T, Mennini T
Neurobiol Dis, March 2008 …
December,
2007
Phosphorylation-dependent Dimerization And Subcellular Localization Of Islet-brain 1/c-Jun N-terminal Kinase-interacting Protein 1.
Borsello T, Centeno C, Riederer IM, Haefliger JA, Riederer BM
J Neurosci Res., December 2007 …
August,
2007
Time-Course Of C-Jun N-Terminal Kinase Activation After Cerebral Ischemia And Effect Of D-JNKI1 On C-Jun And Caspase-3 Activation
Repici M, Centeno C, Tomasi S, Forloni G, Bonny C, Vercelli A, Borsello T
Neuroscience, August 2007 …
July,
2007
The TAT-JNK Inhibitor Peptide Interferes With Beta Amyloid Protein Stability
Colombo A, Repici M, Pesaresi M, Santambrogio S, Forloni G, Borsello T
Cell Death Differ., July 2007 …
July,
2007
Neuronal Death And Neuroprotection: A Review. Repici M, Mariani J, Borsello T.
Repici M, Mariani J, Borsello T
Methods Mol Biol. 2007;399:1-14. Review., July 2007
June,
2007
JNK Signalling: A Possible Target To Prevent Neurodegeneration
Borsello T, Forloni G
Current Pharmaceutical Design, 13, 1875-1886, June 2007 …
June,
2007
Editor Of The Volume Neuroprotection: Methods In Molecular Biology Published By Humana Press, USA
Borsello T
Methods in Molecular Biology, June 2007
December,
2006
JNK Pathway As Therapeutic Target To Prevent Degeneration In The Central Nervous System
Repici M, Borsello T
Adv Exp Med Biol. 588:145-55, December 2006 …
June,
2006
Role Of The JNK Pathway In NMDA-Mediated Excitotoxicity Of Cortical Neurons
Centeno C, Repici M, Chatton JY, Riederer BM, Bonny C, Nicod P, Price M, Clarke PG, Papa S, Franzoso G, Borsello T
Cell Death Differ., June 2006 …
June,
2006
Targeting Stress Activated Protein Kinases, JNK And P38, As New Therapeuyic Approach For Neurodegenerative Diseases
Bendotti C, Tortarolo M, Borsello T
Central Neurvous System Agents in Medical Chemistry 6, 109-117., June 2006 …
March,
2006
A Peptide C-Jun N-Terminal Kinase (JNK) Inhibitor Blocks Mechanical Allodynia After Spinal Nerve Ligation: Respective Roles Of JNK Activation In Primary Sensory Neurons And Spinal Astrocytes For Neuropathic Pain Development And Maintenance
Zhuang ZY, Wen YR, Zhang DR, Borsello T, Bonny C, Strichartz GR, Decosterd I, Ji RR
Neuroscience 26(13):3551-60, March 2006 …
June,
2005
Targeting The JNK Pathway For Therapeutic Protective Strategies In The Nervous System Diseases
Bonny C, Borsello T, Zine A
Neruroscience (Review), 6(1):57-67., June 2005
November,
2004
Intracellular Stress Signalling Pathways Activated During Human Islet Preparation And Following Acute Cytokine Exposure
Abdelli S, Ansite J, Roduit R, Borsello T, Matsumoto I, Sawada T, Allaman-Pillet N, Henry H, Beckmann JS, Hering BR, Bonny C
Diabetes, Vol 53, November 2004 …
October,
2004
The Cell Permeable Peptides Strategy Is A Promising New Tool For The Prevention Of Neurodegeneration
Borsello T
Discovery Medicine, Vol 4 Issue 23, October 2004 …
May,
2004
Use Of Cell-Permeable Peptides To Prevent Neuronal Degeneration
Borsello T, Bonny C
Trends Mol Med., 10(5):239-244., May 2004 …
October,
2003
Kainate-Induced Endocytosis In Retinal Amacrine Cells
Borsello T, Bressoud R, Mottier V, Gonzalez N, Gomez G, Clarke PG
J Comp Neurol., 465(2):286-95., October 2003 …
September,
2003
A Peptide Inhibitor Of C-Jun N-Terminal Kinase Protects Against Excitotoxicity And Cerebral Ischemia
Borsello T, Clarke PG, Hirt L, Vercelli A, Repici M, Schorderet DF, Bogousslavsky J, Bonny C
Nat Med., (9):1180-6, September 2003 …
August,
2003
N-Methyl-D-Aspartate-Triggered Neuronal Death In Organotypic Hippocampal Cultures Is Endocytic, Autophagic And Mediated By The C-Jun N-Terminal Kinase Pathway
Borsello T, Croquelois K, Hornung JP, Clarke PG
Eur J Neurosci., 18(3):473-85., August 2003 …
November,
2002
Ultrastructure Of Retinal Ganglion Cell Death After Axotomy In Chick Embryos
Borsello T, Mottier V, Castagne V, Clarke PG
J Comp Neurol., 25;453(4):361-71., November 2002 …
December,
2000
Granule Neuron DNA Damage Following Deafferentation In Adult Rats Cerebellar Cortex: A Lesion Model
Borsello T, Di Luzio A, Ciotti MT, Calissano P, Galli C
Neuroscience, 95(1):163-71., December 2000
November,
1998
Adenosine And ADP Prevent Apoptosis In Cultured Rat Cerebellar Granule Cells
Vitolo OV, Ciotti MT, Galli C, Borsello T, Calissano P
Brain Res., 2;809(2):297-301., November 1998
March,
1994
Exposure To Kainic Acid Mimics The Effects Of Axotomy In Cerebellar Purkinje Cells Of The Adult Rat
Rossi F, Borsello T, Strata P
Eur J Neurosci., 6(3):392-402., March 1994
January,
1994
Embryonic Purkinje Cells Grafted On The Surface Of The Adult Uninjured Rat Cerebellum Migrate In The Host Parenchyma And Induce Sprouting Of Intact Climbing Fibres
Rossi F, Borsello T, Strata P
Eur J Neurosci., 6(1):121-36., January 1994
November,
1993
Ectopic Purkinje Cells In The Adult Rat: Olivary Innervation And Different Capabilities Of Migration And Development After Grafting
Rossi F, Borsello T
J Comp Neurol., 1;337(1):70-82., November 1993
April,
1993
Regressive Modifications Of Climbing Fibres Following Purkinje Cell Degeneration In The Cerebellar Cortex Of The Adult Rat
Rossi F, Borsello T, Vaudano E, Strata P
Neuroscience, 53(3):759-78., April 1993
April,
1992
Embryonic Purkinje Cells Grafted On The Surface Of The Cerebellar Cortex Integrate In The Adult Unlesioned Cerebellum
Rossi F, Borsello T, Strata P
Eur J Neurosci., 4(6):589-593., April 1992